C96 CRITICAL CARE: NEW DISCOVERIES IN ARDS: Elevated Plasma Concentrations Of Soluble Suppressor Of Tumorigenicity-2 (sst2) Accurately Discriminates Acute Respiratory Distress Syndrome From Acute Heart Failure

Rationale: The distinction between acute heart failure (AHF) and acute respiratory distress syndrome (ARDS), two common causes of acute hypoxemic respiratory failure with considerable morbidity, can be challenging. Serum concentrations of soluble suppressor of tumorigenicity-2 (sST2), a member of th...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Levy, S D, Thompson, B T, Matthay, M A, Januzzi, J L, Christiani, D C, Bajwa, E
Format: Article
Language:English
Subjects:
Heart failure
Respiratory distress syndrome
Respiratory therapy
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Summary:Rationale: The distinction between acute heart failure (AHF) and acute respiratory distress syndrome (ARDS), two common causes of acute hypoxemic respiratory failure with considerable morbidity, can be challenging. Serum concentrations of soluble suppressor of tumorigenicity-2 (sST2), a member of the interleukin-1 receptor family that plays a key role in in both endothelial and epithelial signaling pathways, has been shown to be highly prognostic in ARDS, and may have a diagnostic role as well.
ISSN:1073-449X
1535-4970