A67 BREAKDOWN: THE CELLULAR CONTRIBUTION TO PULMONARY HYPERTENSION: O-Glcnac Transferase Regulates Angiogenesis In Idiopathic Pulmonary Arterial Hypertension

[...]PASMCs and PAECs (pulmonary arterial endothelial cells) from control and PAH patients were co-cultured to form spheroids, and vascular sprouting was assessed after 24 hours. Furthermore, IPAH and control PAEC/PASMC spheroid co-culture models combined in collagen were assessed for vascular sprou...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Barnes, J, Tian, L, Mellor, N E, Comhair, S A, Dweik, R
Format: Article
Language:English
Subjects:
Angiogenesis
Cell cycle
Hypertension
Metabolism
Online Access:Get full text
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Summary:[...]PASMCs and PAECs (pulmonary arterial endothelial cells) from control and PAH patients were co-cultured to form spheroids, and vascular sprouting was assessed after 24 hours. Furthermore, IPAH and control PAEC/PASMC spheroid co-culture models combined in collagen were assessed for vascular sprouting.
ISSN:1073-449X
1535-4970