A35 SEVERE ASTHMA: Chronic Psychosocial Stress Induced Heightened Lymphocyte Activation In Severe Asthmatic Patients

[...]natural killer cells and type 2 innate lymphoid cells (ILC2s) are also found to play an important role in asthma pathogenesis. [...]we aimed to delineate the effect of chronic psychosocial stress on innate and adaptive lymphocyte activation in severe asthmatic patients.Methods: Conclusions: Sev...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Ge, M Q, Tompkins, D G, Flayer, C H, Larson, E D, Killingbeck, S S, Juarez, M, Morrissey, B M, Kenyon, N, Haczku, A
Format: Article
Language:English
Subjects:
Asthma
Dendritic cells
Lymphocytes
Stress
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Summary:[...]natural killer cells and type 2 innate lymphoid cells (ILC2s) are also found to play an important role in asthma pathogenesis. [...]we aimed to delineate the effect of chronic psychosocial stress on innate and adaptive lymphocyte activation in severe asthmatic patients.Methods: Conclusions: Severe asthmatic patients showed heightened stress accompanied by increased recruitment and activation of innate and adaptive lymphocytes, and dendritic cells in the circulation.
ISSN:1073-449X
1535-4970