A21 IMMUNE MECHANISMS OF SARCOIDOSIS AND OTHER GRANULOMATOUS DISEASES: The Association Of Matrix Metalloproteinase-9 Expression With Active Pulmonary And Cutaneous Sarcoidosis

Variables for pulmonary specimens included the number of granulomas per high power field, the percent of lung affected by sarcoidosis, the presence and extent of lymphoid aggregates, diffuse lymphocytic infiltration, and fibrosis. Non-granulomatous diffuse lymphoid aggregates were found predominantl...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Sathiyamoorthy, G, Rosenbach, M A, Shauf, A, Mikaelian, I, Kim, S, O'Riordan, T G, Gossage, D L, Smith, V, Li, M, Baughman, R P, Farver, C, Culver, D A
Format: Article
Language:English
Subjects:
Disease
Inflammation
Sarcoidosis
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Summary:Variables for pulmonary specimens included the number of granulomas per high power field, the percent of lung affected by sarcoidosis, the presence and extent of lymphoid aggregates, diffuse lymphocytic infiltration, and fibrosis. Non-granulomatous diffuse lymphoid aggregates were found predominantly in the explant samples-in these areas macrophages and dendritic cells stained for MMP9.
ISSN:1073-449X
1535-4970