A107 PEDIATRIC CARDIOVASCULAR DISEASE AND CRITICAL CARE: Comparison Of The Dose Response Changes To Effort And Work-Of-Breathing Parameters In An Animal Model Of Extrathoracic Upper Airway Obstruction

Corresponding author's email: rkhemani@chla.usc.edu Introduction Work of Breathing (WOB) measurements may be helpful in a variety of disease conditions, but accurate measurement requires esophageal pressure and spirometry. While it may be possible to substitute calibrated Respiratory Inductance...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Flink, R C, Khemani, R G, Hotz, J, Ross, P, Newth, C J L
Format: Article
Language:English
Subjects:
Airway management
Esophagus
Pediatrics
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Summary:Corresponding author's email: rkhemani@chla.usc.edu Introduction Work of Breathing (WOB) measurements may be helpful in a variety of disease conditions, but accurate measurement requires esophageal pressure and spirometry. While it may be possible to substitute calibrated Respiratory Inductance Plethysmography (RIP) for spirometry in WOB calculations, effort of breathing (EOB) measurements have theoretical advantages over WOB measurements because they require only esophageal pressure, and will account for situations where transpulmonary pressure increases without changes in volume (i.e. intrinsic PEEP).
ISSN:1073-449X
1535-4970