Molecular diagnostics of ocular allergy

Summary Ocular allergies may severely impact on daily activities and overall quality of life. Conventional allergy testing with skin prick tests and circulating serum immunoglobulin E often falls short of identifying the culprit ocular allergens. On the other hand, targeting the ocular milieu may pr...

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Bibliographic Details
Published in:Acta ophthalmologica (Oxford, England) England), 2017-09, Vol.95 (S259), p.n/a
Main Authors: Vitte, J., Baye, A., Batellier, L., Doan, S., Bury, T.
Format: Article
Language:English
Subjects:
Allergens
Allergies
Conjunctivitis
Hay fever
Hypersensitivity
Immunoglobulin E
Immunoglobulins
Peanuts
Quality of life
Skin tests
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Summary:Summary Ocular allergies may severely impact on daily activities and overall quality of life. Conventional allergy testing with skin prick tests and circulating serum immunoglobulin E often falls short of identifying the culprit ocular allergens. On the other hand, targeting the ocular milieu may prove valuable for ocular allergy diagnostics. Conjunctival provocation testing and specific immunoglobulin E detection in tear fluid provide data on local ocular hypersensitivity. We focused on specific IgE testing by means of a commercial allergen microarray (ISAC® 112, Thermo Fisher Scientific). We report here the contribution of allergen microarray testing to identifying the culprit allergen in a 42‐year old woman presenting with perennial allergic conjunctivitis.
ISSN:1755-375X
1755-3768
DOI:10.1111/j.1755-3768.2017.03353