The use of corneal scrubbing associated with matrix therapy in the treatment of chronic ulcers

• Published in: Acta ophthalmologica (Oxford, England) England), 2017-09, Vol.95 (S259), p.n/a
• Main Authors: Lazreg, S., Christophe, B.
• Format: Article
• Language: English
• Subjects: Coloration; Complications; Contact lenses; Cornea; Cotton; Dermatology; Fluorescein; Lubricants; Tissues; Ulcers
• ISSN: 1755-375X; 1755-3768
• DOI: 10.1111/j.1755-3768.2017.0S021

Purpose to treat refractory chronic ulcers with corneal scrubbing and matrix therapy; In dermatology practice, the same method is used in severe burns, the cutaneous scrubbing removes necrotic tissues and helps healthy tissues to progress faster Methods Retrospective study on chronic corneal ulcers evolving for several week refractory to conventional treatments; All the corneal ulcers were scrubbed with cotton buds, most of them received matrix therapy at the dose regimen of a drop every other day until corneal healing and preservative free lubricants 3 times a day, for the painful cases, we performed bandage contact lenses, and the remaining patients received the bandage contact lenses without matrix therapy; ocular examination was performed at D0, D3, D7, D15 and D30, with slit lamp examination, fluorescein coloration and measurement of the size of the ulcers, Results 18 patients were included and divided on 3 groups Group 1: corneal scrubbing, matrix therapy, lubricant and contact lenses Group 2: corneal scrubbing, matrix therapy, lubricant without contact lenses Group 3: corneal scrubbing; lubricant and contact lenses All the ulcers healed at D30, in the group1 and 2, corneal healing was faster between 7 and 10 days. No complications were reported despite the occurrence of one case of descemetocele at D3, with a good outcome at D15 Conclusions Corneal scrubbing may accelerate corneal healing and therefore allows matrix therapy to be more efficient.