Copper‐Catalyzed Sulfonylation of Alkenes and Amines by Using Thiosulfonates as a Sulfonylating Agent

Synthetically and pharmaceutically useful vinyl sulfones and sulfonamides are synthesized by the direct coupling of thiosulfonates with alkenes and amines, respectively. Copper catalysts help to generate the sulfonyl group from thiosulfonates and to form the C(sp2)–S/N–S bonds of the organosulfur co...

Full description

Saved in:
Bibliographic Details
Published in:European journal of organic chemistry 2017-09, Vol.2017 (34), p.5025-5031
Main Authors: Shyam, Pranab K., Son, Soobin, Jang, Hye‐Young
Format: Article
Language:English
Subjects:
Aliphatic compounds
Alkenes
Amines
Aromatic compounds
Chemical bonds
Copper
Homogeneous catalysis
Organosulfur compounds
Sulfonamides
Sulfones
Sulfur
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Synthetically and pharmaceutically useful vinyl sulfones and sulfonamides are synthesized by the direct coupling of thiosulfonates with alkenes and amines, respectively. Copper catalysts help to generate the sulfonyl group from thiosulfonates and to form the C(sp2)–S/N–S bonds of the organosulfur compounds. This paper discusses the scope of these reactions of aromatic and aliphatic thiosulfonates with alkenes and amines. Copper‐catalyzed sulfonyl‐group transfer from thiosulfonates to alkenes and amines has been carried out to give vinyl sulfones and sulfonamides.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201700971