Synthesis of new hydrazones based on o- and p-hydroxybenzohydrazides

o - and p -Hydroxybenzohydrazides reacted with various unsaturated aromatic aldehydes to give the corresponding N ′-(hydroxybenzoyl)hydrazones. Inhibitory activity of the obtained hydrazones against cathepsin E was evaluated.

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Bibliographic Details
Published in:Russian journal of general chemistry 2017-08, Vol.87 (8), p.1707-1710
Main Authors: Nurkenov, O. A., Satpaeva, Zh. B., Shchepetkin, I. A., Fazylov, S. D., Seilkhanov, T. M., Akhmetova, S. B.
Format: Article
Language:English
Subjects:
Aldehydes
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Hydrazones
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Description
Summary:o - and p -Hydroxybenzohydrazides reacted with various unsaturated aromatic aldehydes to give the corresponding N ′-(hydroxybenzoyl)hydrazones. Inhibitory activity of the obtained hydrazones against cathepsin E was evaluated.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363217080114