Stem Cells: Controlled Exposure of Bioactive Growth Factor in 3D Amyloid Hydrogel for Stem Cells Differentiation (Adv. Healthcare Mater. 18/2017)

Samir K. Maji and co‐workers present an amyloid hydrogel for sustained growth factors delivery in tissue engineering applications in article number 1700368. The image represents stem cells (blue spheres) embedded within the amyloid hydrogel matrix (grey network) encapsulating growth factors (green d...

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Bibliographic Details
Published in:Advanced healthcare materials 2017-09, Vol.6 (18), p.n/a
Main Authors: Das, Subhadeep, Kumar, Rakesh, Jha, Narendra Nath, Maji, Samir K.
Format: Article
Language:English
Subjects:
Amyloid
Biocompatibility
Cell culture
Differentiation
drug delivery
Gene expression
growth factor delivery
Growth factors
Hydrogels
Spheroids
Stem cells
Tissue engineering
Workers
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Summary:Samir K. Maji and co‐workers present an amyloid hydrogel for sustained growth factors delivery in tissue engineering applications in article number 1700368. The image represents stem cells (blue spheres) embedded within the amyloid hydrogel matrix (grey network) encapsulating growth factors (green dots). Within 3D culture, stem cells self‐organizes into spheroids (red sphere) with up‐regulated neural genes. In three‐dimensional cell culture, the entrapped growth factors within hydrogel and the surface property of amyloids promoted stem cells into neuro‐sphere formation and higher neuronal gene expression.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.201770094