Opioid Pharmacology: The Good, the Bad, and the Ugly (P17)

An abstract of a study by Davis and Sloan discussing the benefits of combining opioids, either bifunctional ligands or as opioid combinations, is presented. Peptide bi-functional ligands have proven effective in animal models. Combinations of oxycodone with morphine, sequential use of fentanyl-morph...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pain and symptom management 2017-02, Vol.53 (2), p.311-311
Main Authors: Davis, Mellar, MD FCCP FAAHPM, Sloan, Paul A., MD
Format: Article
Language:English
Subjects:
Anesthesia & Perioperative Care
Animals
Dosage
Ligands
Methadone
Morphine
Narcotics
Opioids
Pain
Pain management
Pain Medicine
Pharmacology
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An abstract of a study by Davis and Sloan discussing the benefits of combining opioids, either bifunctional ligands or as opioid combinations, is presented. Peptide bi-functional ligands have proven effective in animal models. Combinations of oxycodone with morphine, sequential use of fentanyl-morphine, combinations of morphine-methadone in animal models and in clinical studies have demonstrated improved pain responses at lower doses.
ISSN:0885-3924
1873-6513
DOI:10.1016/j.jpainsymman.2016.12.017