Integrated antimicrobial and shape memory zwitterionic copolymers

This paper reports novel antimicrobial properties and shape memory properties of zwitterionic copolymers synthesized with 3-dimethyl(methacyloyloxyethyl) ammonium propane sulfonate (DMAPS) and acrylic acid (AA). The results demonstrate that the DMAPS-co-AA copolymer successfully integrates the antim...

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Bibliographic Details
Published in:Materials letters 2017-02, Vol.189, p.74-77
Main Authors: Chen, Shaojun, Mei, Zhankui, Ren, Huanhuan, Zhuo, Haitao
Format: Article
Language:English
Subjects:
Acrylic acid
Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
Biocompatibility
Biomaterials
Biomedical materials
Chemical synthesis
Copolymers
Drug delivery systems
Materials science
Properties (attributes)
Shape memory
Shape memory materials
Studies
Zwitterionic polymers
Zwitterions
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Summary:This paper reports novel antimicrobial properties and shape memory properties of zwitterionic copolymers synthesized with 3-dimethyl(methacyloyloxyethyl) ammonium propane sulfonate (DMAPS) and acrylic acid (AA). The results demonstrate that the DMAPS-co-AA copolymer successfully integrates the antimicrobial properties and shape memory properties. The zwitterionic copolymer has good antimicrobial activity with bacteriostasis mechanism. Though the minimal inhibition concentration (MIC) of DMAPS-co-AA copolymer is much higher, zwitterionic copolymer is a good candidate of environmental friendly antimicrobial agent due to its nontoxic and biocompatibility. The shape memory properties of zwitterionic copolymer further encourage them many smart biomedical applications, such as suture and drug release. [Display omitted] •The DMAPS-co-AA copolymer successfully integrates antibacterial properties and shape memory properties.•The zwitterionic copolymer has good antimicrobial activity with bacteriostasis mechanism.•The shape memory properties of zwitterionic copolymer encourage them many smart biological applications.
ISSN:0167-577X
1873-4979
DOI:10.1016/j.matlet.2016.11.019