Formulation and evaluation of antibacterial herbal gels of Murraya koenigii leaves extract

The gel formulations were prepared by using Carbapol 940, Murraya koenigii leaf extract, propylene glycol, methyl paraben, propyl paraben, glycerine and required amount of distilled water. There is a continuous and urgent need to discover new antimicrobial compounds with diverse chemical structures...

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Bibliographic Details
Published in:Research journal of pharmacy and technology 2017, Vol.10 (6), p.1798
Main Authors: Sandeep, D.S., Nayak, Prashant, Jose, Jobin, Relita, M. Rishal, Sumana, D. R.
Format: Article
Language:English
Subjects:
Antimicrobial agents
Herbal medicine
Leaves
Medicine
Polymers
Skin
Studies
Trees
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Summary:The gel formulations were prepared by using Carbapol 940, Murraya koenigii leaf extract, propylene glycol, methyl paraben, propyl paraben, glycerine and required amount of distilled water. There is a continuous and urgent need to discover new antimicrobial compounds with diverse chemical structures and novel mechanism of action due to an alarming increase in the influence of new and reemerging infectious diseases and development of resistance to the antibiotics in current clinical use3. The pH of all the formulated herbal gels was measured by using digital pH meter.10 Viscosity: Viscosity of herbal gels was determined by using Brookfield rotational viscometer at 100 rpm using spindle no.64.10 Spreadability: The spreadability of gel formulations was determined by measuring the spreading diameter of 1g of gel between two horizontal plates.11 Antibacterial activity: [...]from the overall results, finally it was concluded that the formulated herbal gels have significant antimicrobial properties and hence will be better, safe and effective than allopathic medications.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.5958/0974-360X.2017.00317.1