Joint genome-wide association analysis of continuous and discrete traits

An abstract of a study by Sumreddee et al examining joint genome-wide association analysis of continuous and discrete traits is presented. Genome-wide association studies (GWAS) are becoming a standard tool for the genetic dissection of complex traits and for the estimation of genomically enhanced b...

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Bibliographic Details
Published in:Journal of animal science 2017-08, Vol.95, p.104
Main Authors: Sumreddee, P, Toghiani, S, Aggrey, S E, Rekaya, R
Format: Article
Language:English
Subjects:
Animal breeding
Association analysis
Breeding of animals
Dissection
Genetics
Genome-wide association studies
Genomes
Genomics
Livestock
Regression analysis
Regression models
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Summary:An abstract of a study by Sumreddee et al examining joint genome-wide association analysis of continuous and discrete traits is presented. Genome-wide association studies (GWAS) are becoming a standard tool for the genetic dissection of complex traits and for the estimation of genomically enhanced breeding values. Although linear regression models for implementation of association studies were used to analyze continuous and discrete responses, their implementation was always in a univariate context. Arguably, the joint analysis of continuous and discrete traits in GWAS will be advantageous because of a better use of available information and the existing correlation structure among traits.
ISSN:0021-8812
1525-3163