Reverse Phase-HPLC Method for Simultaneous Estimation of Tetracaine and Oxymetazoline in Bulk Samples

Various analytical techniques have been used for the determination of Tetracaine HCl which include high-performance liquid chromatography [2,5,6,16-19] , Spectrometry [3,9-11,23], Fluorescene [4,7,8], capillary electrophoresis [12, 14], voltametry [13], gas chromatography [15,20-22] and for the dete...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences and research 2017-09, Vol.9 (9), p.1589
Main Authors: Sreelakshmi, M, Sasidhara, R L C, Raviteja, B
Format: Article
Language:English
Subjects:
Acids
Chromatography
Ethanol
Ions
Mass spectrometry
Membrane filters
Molecular weight
Pharmaceuticals
Scientific imaging
Sensors
Software
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Summary:Various analytical techniques have been used for the determination of Tetracaine HCl which include high-performance liquid chromatography [2,5,6,16-19] , Spectrometry [3,9-11,23], Fluorescene [4,7,8], capillary electrophoresis [12, 14], voltametry [13], gas chromatography [15,20-22] and for the determination of Oxymetazoline hydrochloride which include HPLC [25,26,31], spectroscopy [27, 28-30] methods have been used in the determination of concentration of Tetracaine HCl and Oxymetazoline hydrochloride in pharmaceutical preparations. [...]the present work was aimed to develop Simple, sensitive and reproducible RP-HPLC method for the determination of oxymetazoline hydrochloride in bulk ( API) samples by RP-HPLC method. [...]the developed method was specific. [...]the developed method is accurate throughout the selected range.
ISSN:0975-1459