Impact of type 2 diabetes mellitus on short term and working memory

Initially, data were tested for normality using Kolmogorov-Smirnov test and Shapirowik Test. Since the data do not follow normal distribution, nonparametric tests were used which include Mann-Whitney G-test and correlationregression analysis was performed using Spearman rank correlation. [7] Alka et...

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Bibliographic Details
Published in:National journal of physiology, pharmacy and pharmacology pharmacy and pharmacology, 2017, Vol.7 (10), p.1
Main Authors: G, Mythri, M, Girish, L, Manjunath
Format: Article
Language:English
Subjects:
Age
Aging
Cognition & reasoning
Cognitive ability
Dementia
Diabetes
Gender
Hyperglycemia
Hypoglycemia
Insulin resistance
Memory
Older people
Short term
Statistical analysis
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Summary:Initially, data were tested for normality using Kolmogorov-Smirnov test and Shapirowik Test. Since the data do not follow normal distribution, nonparametric tests were used which include Mann-Whitney G-test and correlationregression analysis was performed using Spearman rank correlation. [7] Alka et al. conducted 4 years prospective study on 999 white men and women aged 42-89 years according to their blood glucose levels, applied three tests, viz.; Mini-mental state examination, VFT and trial marking ß-test and concluded that women with DM had 4 fold increased risk of a major cognitive decline on the VFT when compared with women without diabetes. [16] Limitations Prospective studies are required to examine the putative link between noninsulin dependent diabetes and cognitive dysfunction, because only by using such study designs can a causal relationship be established. Since different studies have utilized different psychological tests, there is a need to develop a standard study design that can be employed in testing cognitive impairment in type 2 diabetes. The main hypothesis to explain the decline in memory status in diabetic patients with respect to duration, gender, age, blood sugar levels, and glycemic control are hyperglycemia, hypoglycemia, microvascular injury, insulin resistance, or hyperinsulinemia.
ISSN:2320-4672
2231-3206
DOI:10.5455/njppp.2017.7.0413823052017