Proximal subungual onychomycosis caused by Aspergillus flavus in a HIV-positive patient

PSO is uncommon in the general population but is frequently associated with human immunodeficiency virus (HIV) infection and is mostly caused by Trichophyton rubrum and Trichophyton megninii. The final diagnosis was peripheral neuropathy with seborrhoeic dermatitis, oral candidiasis and PSO due to A...

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Published in:Indian journal of dermatology, venereology, and leprology venereology, and leprology, 2009-07, Vol.75 (4), p.410
Main Authors: Choudhary, Sanjiv V, Koley, Sankha, Mallick, Sanjay, Bose, Seema, Basak, Silpi
Format: Article
Language:English
Subjects:
Adult
Aspergillosis - complications
Aspergillosis - diagnosis
Aspergillus
Aspergillus flavus
Care and treatment
Causes of
Diagnosis
Health aspects
HIV
HIV patients
HIV Seropositivity - complications
HIV Seropositivity - diagnosis
HIV-1
Human immunodeficiency virus
Humans
Male
Mucous membrane
Onychomycosis
Onychomycosis - complications
Onychomycosis - diagnosis
Patients
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Summary:PSO is uncommon in the general population but is frequently associated with human immunodeficiency virus (HIV) infection and is mostly caused by Trichophyton rubrum and Trichophyton megninii. The final diagnosis was peripheral neuropathy with seborrhoeic dermatitis, oral candidiasis and PSO due to Aspergillus flavus of the left great toe in an HIV-positive patient. [8],[9],[10] In our case, Aspergillus flavus species was the pathogen and not a contaminant as (1) KOH examination of nail scrapings revealed a septate branching mycelium, (2) three repeated cultures performed on Sabouraud's dextrose agar with chloramphenicol revealed characteristic morphology and color suggestive of Aspergillus flavus and (3) slide culture findings were suggestive of Aspergillus flavus only.
ISSN:0378-6323
0973-3922
1998-3611
DOI:10.4103/0378-6323.53152