Fabrication, characterization, and antifungal activity of sodium hyaluronate-TiO^sub 2^ bionanocomposite against Aspergillus niger

In this study, characterization and antifungal properties of novel sodium hyaluronate-TiO2 bionanocomposite were studied. Sodium hyaluronate (SH) biopolymer was synthesized by bacterial fermentation, while TiO2 nanoparticles and SH-TiO2 nanocomposites were synthesized using the sol-gel and in-situ m...

Full description

Saved in:
Bibliographic Details
Published in:Materials letters 2017-11, Vol.207, p.113
Main Authors: Safaei, Mohsen, Taran, Mojtaba
Format: Article
Language:English
Subjects:
Bacteria
Biomedical materials
Biopolymers
Electron microscopy
Energy transmission
Fermentation
Fungicides
Materials science
Nanocomposites
Nanoparticles
Sodium
Sol-gel processes
Studies
Synthesis
Titanium oxides
Transmission electron microscopy
X ray powder diffraction
X-ray spectroscopy
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this study, characterization and antifungal properties of novel sodium hyaluronate-TiO2 bionanocomposite were studied. Sodium hyaluronate (SH) biopolymer was synthesized by bacterial fermentation, while TiO2 nanoparticles and SH-TiO2 nanocomposites were synthesized using the sol-gel and in-situ methods, respectively. The characterizations of products were surveyed by ultravioletvisible spectroscopy (UVvis), X-ray powder diffraction (XRD), transmission electron microscopy (TEM), and energy dispersive X-ray spectroscopy (EDS). Appling these techniques, we identified some differences in the nanocomposite structure and its components that confirmed the formation of the SH-TiO2 nanocomposite. SH-TiO2 nanocomposites showed better antifungal activity against Aspergillus niger compared to sodium hyaluronate biopolymer and TiO2 nanoparticles. The improved antifungal activity of the SH-TiO2 bionanocomposite may be elucidated by a synergistic antifungal effect.
ISSN:0167-577X
1873-4979