Biological activity of phytosterols and their derivatives

This review is devoted to contemporary status of investigation of C-29 and C-28 plant sterols (phytosterols) in relation to their biological activity in mammals and mammalian cells. On the basis of experimental studies published during the last decade the following questions are discussed: phytoster...

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Bibliographic Details
Published in:Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry Biomedical chemistry, 2008, Vol.2 (1), p.1-17
Main Authors: Mehtiev, A. R., Misharin, A. Yu
Format: Article
Language:English
Subjects:
Bioorganic Chemistry
Chemistry
Chemistry and Materials Science
Medicinal Chemistry
Reviews
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Summary:This review is devoted to contemporary status of investigation of C-29 and C-28 plant sterols (phytosterols) in relation to their biological activity in mammals and mammalian cells. On the basis of experimental studies published during the last decade the following questions are discussed: phytosterols and nutrition; phytosterols and body cholesterol level; phytosterols and intestinal absorption of lipids, the role of phytosterols in lipid metabolism regulation; phytosterols and cultured mammalian cells; products of phytosterols oxidation; phytoecdysteroids and induced gene expression.
ISSN:1990-7508
1990-7516
DOI:10.1007/s11828-008-1001-4