Endobronchial plasmacytoma in patient with multiple myeloma

• Published in: The clinical respiratory journal 2017-11, Vol.11 (6), p.1057-1059
• Main Authors: Sunnetcioglu, Aysel, Ekin, Selami, Bayram, Irfan, Ekinci, Omer, Bugday, Inci Bahadır
• Format: Article
• Language: English
• Subjects: Bone Marrow Neoplasms - pathology; Bronchi - pathology; Bronchial Neoplasms - diagnostic imaging; Bronchial Neoplasms - metabolism; Bronchial Neoplasms - pathology; bronchoscopy; Bronchoscopy - methods; endobronchial; Female; Humans; Lung - diagnostic imaging; Lung - pathology; Lung Neoplasms - pathology; Middle Aged; Multiple myeloma; Multiple Myeloma - complications; Multiple Myeloma - diagnosis; Multiple Myeloma - pathology; plasmacytoma; Plasmacytoma - diagnosis; Plasmacytoma - metabolism; Plasmacytoma - pathology; Pleural Effusion - diagnosis; Pulmonary Atelectasis - diagnostic imaging; Pulmonary Atelectasis - etiology; Tomography, X-Ray Computed
• ISSN: 1752-6981; 1752-699X
• DOI: 10.1111/crj.12408

Endobronchial plasmacytoma is a rare manifestation of extramedullary plasmacytoma. A 49‐year‐old woman with a history of multiple myeloma consulted to our pulmonary service with progressive dyspnoea and cough and abnormal chest X‐ray. A lesion measuring 6 × 5 cm in size existed in anterior baseline of the right lung's lower lobe in thoracic computed tomography in addition to right bronchial narrowing and atelectasis distal in lesions. Diagnostic bronchoscopy was performed previously for the obstruction and biopsy was taken from the lesion in the right middle lobe bronchus. Endobronchial biopsies showed extensive tumour infiltration with plasmocytoid cells. Immunohistochemistry was positive CD138 and Lamda. Microscopic and immunohistochemical findings supported the diagnosis of extramedullary endobronchial plasmacytoma.