Preparation and Characteristics of Nanostructured Lipid Carrier (NLC) Loaded Red Ginger Extract Using High Pressure Homogenizer Method

[...]as an alternative, NLC is developed as it is composed of a solid lipid matrix with the specific content of liquid lipid which is useful to increase the solubility of the lipophilic compound [4]. [...]this study analyzes the effect of HPH on properties of the production of red ginger encapsulate...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences and research 2017-10, Vol.9 (10), p.1889-1893
Main Authors: Sadiah, Siti, Anwar, Effionora, Djufri, Mahdi, Cahyaningsih, Umi
Format: Article
Language:English
Subjects:
Biomarkers
Efficiency
Laboratories
Lipids
Methods
Particle size
Solvents
Surfactants
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Summary:[...]as an alternative, NLC is developed as it is composed of a solid lipid matrix with the specific content of liquid lipid which is useful to increase the solubility of the lipophilic compound [4]. [...]this study analyzes the effect of HPH on properties of the production of red ginger encapsulated nanostructured lipid carrier (RG-NLC), particularly on its size. [...]on F8 even with the same lipid composition but with 4% extract of ginger to be not similar with the amount of extract of ginger floating on the surface after mixing with Ultraturax with speed 10.000 rpm for 15 minutes. [...]the formulation of a further process with a high-pressure homogenizer (HPH) is a formula F7 containing red ginger extract is higher than F6. The five types of HPH cycles in general both four cycles up to 20 cycles result in particle size, polydispersion index and zeta potential eligible. [...]Formula with fourcycle become one of choice with consideration of process efficiency.
ISSN:0975-1459