Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery

Invited for the cover of this issue is the group of Pavel K. Mykhailiuk at the Taras Shevchenko National University of Kyiv and Enamine Ltd. The image depicts spirocyclic pyrrolidine—a novel building block for drug discovery. Read the full text of the article at 10.1002/chem.201702362. “…we were ver...

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Published in:Chemistry : a European journal 2017-11, Vol.23 (66), p.16695-16695
Main Authors: Chalyk, Bohdan A., Butko, Maryna V., Yanshyna, Oksana O., Gavrilenko, Konstantin S., Druzhenko, Tetiana V., Mykhailiuk, Pavel K.
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Chemistry
Pyrrolidine
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container_end_page 16695
container_issue 66
container_start_page 16695
container_title Chemistry : a European journal
container_volume 23
creator Chalyk, Bohdan A.
Butko, Maryna V.
Yanshyna, Oksana O.
Gavrilenko, Konstantin S.
Druzhenko, Tetiana V.
Mykhailiuk, Pavel K.
description Invited for the cover of this issue is the group of Pavel K. Mykhailiuk at the Taras Shevchenko National University of Kyiv and Enamine Ltd. The image depicts spirocyclic pyrrolidine—a novel building block for drug discovery. Read the full text of the article at 10.1002/chem.201702362. “…we were very much impressed by the high practical potential of the developed procedure: from every cyclic ketone, a variety of spirocyclic pyrrolidines can be obtained.” Read more about the story behind the cover in the Cover Profile and about the research itself on page 16782 ff. (DOI: 10.1002/chem.201702362).
doi_str_mv 10.1002/chem.201704330
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Pyrrolidine
title Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery
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