Candida haemulonii sensu lato: Update of the Determination of Susceptibility Profile in Argentina and Literature Review

Purpose of review This review summarizes the information available of Candida haemulonii sensu lato, and updates the in vitro susceptibility profile of the isolates of these species from Argentina. C. haemulonii sensu lato causes fungemia in low frequency in adults and children; however, the knowled...

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Bibliographic Details
Published in:Current fungal infection reports 2017-12, Vol.11 (4), p.203-208
Main Authors: Isla, Guillermina, Taverna, Constanza G., Szusz, Wanda, Vivot, Walter, García-Effron, Guillermo, Davel, Graciela
Format: Article
Language:English
Subjects:
Bayesian analysis
Breakpoints
Candida
Children
Clinical Mycology Lab Issues (S Córdoba
Fungemia
Infectious Diseases
Internal Medicine
Literature reviews
Medicine
Medicine & Public Health
Occupational Medicine/Industrial Medicine
Pneumology/Respiratory System
Reviews
Section Editor
Topical Collection on Clinical Mycology Lab Issues
Tropical Medicine
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Summary:Purpose of review This review summarizes the information available of Candida haemulonii sensu lato, and updates the in vitro susceptibility profile of the isolates of these species from Argentina. C. haemulonii sensu lato causes fungemia in low frequency in adults and children; however, the knowledge about this emerging yeast is relevant since it is considered as a multi-resistant pathogen. Recent findings The discovery of new antifungal molecules, the determination of epidemiological cutoff value and clinical breakpoints for some yeasts of clinical impact, and the update of techniques to determine the in vitro susceptibility profile to yeast have generated some available information, although, for C. haemulonii sensu lato, this information is not always useful for clinical application. Summary We determined the susceptibility profile of C. haemulonii sensu lato strains isolated in Argentina, as a first step to establish the epidemiological cutoff values in our region. We also review the current situation in other countries.
ISSN:1936-3761
1936-377X
DOI:10.1007/s12281-017-0300-y