Nutritional Status of Hematological Patients before Hematopoietic Stem Cell Transplantation and in Early Posttransplantation Period

Hematopoietic stem cell transplantation (HSCT) is an aggressive method of treatment affecting patient's homeostasis. The aim of the study was to evaluate the initial nutritional status of HSCT patients and nutritional status in early posttransplantation period. The prospective study included 10...

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Bibliographic Details
Published in:Nutrition and cancer 2017-11, Vol.69 (8), p.1205-1210
Main Authors: Krawczyk, Joanna, Kraj, Leszek, Korta, Teresa, Wiktor-Jędrzejczak, Wiesław
Format: Article
Language:English
Subjects:
Anthropometry
Body mass
Body mass index
Body size
Hematology
Hematopoietic stem cells
Homeostasis
Mucositis
Nutrition assessment
Nutritional status
Patients
Stem cell transplantation
Stem cells
Transferrin
Transferrins
Transplantation
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Summary:Hematopoietic stem cell transplantation (HSCT) is an aggressive method of treatment affecting patient's homeostasis. The aim of the study was to evaluate the initial nutritional status of HSCT patients and nutritional status in early posttransplantation period. The prospective study included 100 consecutive patients with hematological malignancies subjected to HSCT. The nutritional status evaluation was made using the nutritional screening scales, anthropometric and biochemical parameters, as well. On the day +7 following HSCT significant decrease in concentration of total protein (5.8 g/dl), albumin (3.6 g/dl) and transferrin (165 mg/dl) were observed (P < 0.001), although the mean body mass/BMI were within the normal range. On the day +14, the biochemical parameters of the nutritional status were even lower (P < 0.001). Poorer nutritional status was associated with worse performance status and mucositis escalation. The adequate nutritional support plan is important element of the whole transplantation procedure.
ISSN:0163-5581
1532-7914
DOI:10.1080/01635581.2017.1367937