Synthesis, physical properties and premliminary investigation of hemocompatibility of polyurethanes from aliphatic resources with castor oil participation

The synthesis of polyurethanes (PURs) from oligoetherdiol, two low molecular diols, castor oil and 4,4'-Methylenebis(cyclohexylisocyanate) is described. These polymers are characterized by measurements of the mechanical bulk and surface properties, preliminary investigation of compatibility wit...

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Bibliographic Details
Published in:Journal of biomaterials applications 2003-01, Vol.17 (3), p.221
Main Authors: Szelest-Lewandowska, A, Masiulanis, B, Klocke, A, Glasmacher, B
Format: Article
Language:English
Online Access:Get full text
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Summary:The synthesis of polyurethanes (PURs) from oligoetherdiol, two low molecular diols, castor oil and 4,4'-Methylenebis(cyclohexylisocyanate) is described. These polymers are characterized by measurements of the mechanical bulk and surface properties, preliminary investigation of compatibility with human blood and calcification in static conditions. The critical surface energy of synthesized PURs is similar to the critical surface energy of natural surfaces. Material-induced hemolysis and the changes of platelet counts in blood samples after contact with PURs are very low. Static seven-weeks-calcification testing in a synthetic calcification fluid did not indicate calcification by optical density measurements and by visual inspection and computer image processing of the X-ray films for PURs with and without castor oil.
ISSN:0885-3282
1530-8022