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Assessment of the health status and risk of genotoxic and cytotoxic damage in Argentinian adolescents living near horticultural crops
In some rural areas in Argentina, adolescents may be considered as a group indirectly exposed to agrochemicals because their parents plant small crops near their homes. This could become a health risk to children and adolescents who may be more sensitive to exposure to chemicals than adults. The obj...
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| Published in: | Environmental science and pollution research international 2018-02, Vol.25 (6), p.5950-5959 |
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| creator | Martínez-Perafán, Fabián Santoli, María Fernanda López-Nigro, Marcela Carballo, Marta Ana |
| description | In some rural areas in Argentina, adolescents may be considered as a group indirectly exposed to agrochemicals because their parents plant small crops near their homes. This could become a health risk to children and adolescents who may be more sensitive to exposure to chemicals than adults. The objective of this study was to evaluate the health status of two different groups of Argentinian adolescents using biochemical parameters, dietary information, and cytogenetic biomarkers of genotoxicity and cytotoxicity. The study groups included 32 adolescents from Montecarlo, who were indirectly exposed to agrochemicals, and 30 unexposed adolescents from Exaltación de la Cruz. The values of total cholesterol, LDL cholesterol, triglycerides, gamma glutamyltransferase, and butyrylcholinesterase (BuChE) were higher (
p
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| doi_str_mv | 10.1007/s11356-017-0969-z |
| format | article |
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p
< 0.05) in males from Exaltación de la Cruz compared with those from Montecarlo. The BuChE activity was also higher (
p
< 0.05) in females from this region. Furthermore, the consumption of citrus, vegetable-like fruits, tubers, and red meat was more frequent (
p
< 0.05) in Montecarlo. On the other hand, differences in frequency of biomarkers of genetic damage in lymphocytes were not found (
p
> 0.05). However, the cytome assay in buccal cells showed that karyorrhectic and pyknotic cells were more frequent (
p
< 0.05) in the Montecarlo group; whereas, the frequencies of cells with nuclear buds, condensed chromatin and karyolysis were higher (
p
< 0.05) in the Exaltación de la Cruz group. Despite the differences between the parameters and biomarkers evaluated, the adolescents of Montecarlo did not present health impairment probably due to the type and level of exposure to agrochemicals.</description><identifier>ISSN: 0944-1344</identifier><identifier>EISSN: 1614-7499</identifier><identifier>DOI: 10.1007/s11356-017-0969-z</identifier><identifier>PMID: 29235034</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adolescents ; Adults ; Agrochemicals ; Aquatic Pollution ; Atmospheric Protection/Air Quality Control/Air Pollution ; Biomarkers ; Children ; Cholesterol ; Chromatin ; Chromosome aberrations ; Crops ; Cytotoxicity ; Earth and Environmental Science ; Ecotoxicology ; Environment ; Environmental Chemistry ; Environmental Health ; Environmental science ; Exposure ; Genotoxicity ; Health risk assessment ; Health risks ; Horticultural crops ; Low density lipoprotein ; Lymphocytes ; Meat ; Parents ; Research Article ; Rural areas ; Teenagers ; Toxicity ; Triglycerides ; Tubers ; Waste Water Technology ; Water Management ; Water Pollution Control</subject><ispartof>Environmental science and pollution research international, 2018-02, Vol.25 (6), p.5950-5959</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2017</rights><rights>Environmental Science and Pollution Research is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c425t-aa2c9decdef21c3888a78cbc6e0050e892b5f73d0dc8c393c7fb37a2fd1cfd653</citedby><cites>FETCH-LOGICAL-c425t-aa2c9decdef21c3888a78cbc6e0050e892b5f73d0dc8c393c7fb37a2fd1cfd653</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1975832681/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1975832681?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,11688,27924,27925,36060,44363,74895</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29235034$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Martínez-Perafán, Fabián</creatorcontrib><creatorcontrib>Santoli, María Fernanda</creatorcontrib><creatorcontrib>López-Nigro, Marcela</creatorcontrib><creatorcontrib>Carballo, Marta Ana</creatorcontrib><title>Assessment of the health status and risk of genotoxic and cytotoxic damage in Argentinian adolescents living near horticultural crops</title><title>Environmental science and pollution research international</title><addtitle>Environ Sci Pollut Res</addtitle><addtitle>Environ Sci Pollut Res Int</addtitle><description>In some rural areas in Argentina, adolescents may be considered as a group indirectly exposed to agrochemicals because their parents plant small crops near their homes. This could become a health risk to children and adolescents who may be more sensitive to exposure to chemicals than adults. The objective of this study was to evaluate the health status of two different groups of Argentinian adolescents using biochemical parameters, dietary information, and cytogenetic biomarkers of genotoxicity and cytotoxicity. The study groups included 32 adolescents from Montecarlo, who were indirectly exposed to agrochemicals, and 30 unexposed adolescents from Exaltación de la Cruz. The values of total cholesterol, LDL cholesterol, triglycerides, gamma glutamyltransferase, and butyrylcholinesterase (BuChE) were higher (
p
< 0.05) in males from Exaltación de la Cruz compared with those from Montecarlo. The BuChE activity was also higher (
p
< 0.05) in females from this region. Furthermore, the consumption of citrus, vegetable-like fruits, tubers, and red meat was more frequent (
p
< 0.05) in Montecarlo. On the other hand, differences in frequency of biomarkers of genetic damage in lymphocytes were not found (
p
> 0.05). However, the cytome assay in buccal cells showed that karyorrhectic and pyknotic cells were more frequent (
p
< 0.05) in the Montecarlo group; whereas, the frequencies of cells with nuclear buds, condensed chromatin and karyolysis were higher (
p
< 0.05) in the Exaltación de la Cruz group. Despite the differences between the parameters and biomarkers evaluated, the adolescents of Montecarlo did not present health impairment probably due to the type and level of exposure to agrochemicals.</description><subject>Adolescents</subject><subject>Adults</subject><subject>Agrochemicals</subject><subject>Aquatic Pollution</subject><subject>Atmospheric Protection/Air Quality Control/Air Pollution</subject><subject>Biomarkers</subject><subject>Children</subject><subject>Cholesterol</subject><subject>Chromatin</subject><subject>Chromosome aberrations</subject><subject>Crops</subject><subject>Cytotoxicity</subject><subject>Earth and Environmental Science</subject><subject>Ecotoxicology</subject><subject>Environment</subject><subject>Environmental Chemistry</subject><subject>Environmental Health</subject><subject>Environmental science</subject><subject>Exposure</subject><subject>Genotoxicity</subject><subject>Health risk assessment</subject><subject>Health risks</subject><subject>Horticultural crops</subject><subject>Low density lipoprotein</subject><subject>Lymphocytes</subject><subject>Meat</subject><subject>Parents</subject><subject>Research Article</subject><subject>Rural areas</subject><subject>Teenagers</subject><subject>Toxicity</subject><subject>Triglycerides</subject><subject>Tubers</subject><subject>Waste Water Technology</subject><subject>Water Management</subject><subject>Water Pollution 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Edition</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><jtitle>Environmental science and pollution research international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martínez-Perafán, Fabián</au><au>Santoli, María Fernanda</au><au>López-Nigro, Marcela</au><au>Carballo, Marta Ana</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of the health status and risk of genotoxic and cytotoxic damage in Argentinian adolescents living near horticultural crops</atitle><jtitle>Environmental science and pollution research international</jtitle><stitle>Environ Sci Pollut Res</stitle><addtitle>Environ Sci Pollut Res Int</addtitle><date>2018-02-01</date><risdate>2018</risdate><volume>25</volume><issue>6</issue><spage>5950</spage><epage>5959</epage><pages>5950-5959</pages><issn>0944-1344</issn><eissn>1614-7499</eissn><abstract>In some rural areas in Argentina, adolescents may be considered as a group indirectly exposed to agrochemicals because their parents plant small crops near their homes. This could become a health risk to children and adolescents who may be more sensitive to exposure to chemicals than adults. The objective of this study was to evaluate the health status of two different groups of Argentinian adolescents using biochemical parameters, dietary information, and cytogenetic biomarkers of genotoxicity and cytotoxicity. The study groups included 32 adolescents from Montecarlo, who were indirectly exposed to agrochemicals, and 30 unexposed adolescents from Exaltación de la Cruz. The values of total cholesterol, LDL cholesterol, triglycerides, gamma glutamyltransferase, and butyrylcholinesterase (BuChE) were higher (
p
< 0.05) in males from Exaltación de la Cruz compared with those from Montecarlo. The BuChE activity was also higher (
p
< 0.05) in females from this region. Furthermore, the consumption of citrus, vegetable-like fruits, tubers, and red meat was more frequent (
p
< 0.05) in Montecarlo. On the other hand, differences in frequency of biomarkers of genetic damage in lymphocytes were not found (
p
> 0.05). However, the cytome assay in buccal cells showed that karyorrhectic and pyknotic cells were more frequent (
p
< 0.05) in the Montecarlo group; whereas, the frequencies of cells with nuclear buds, condensed chromatin and karyolysis were higher (
p
< 0.05) in the Exaltación de la Cruz group. Despite the differences between the parameters and biomarkers evaluated, the adolescents of Montecarlo did not present health impairment probably due to the type and level of exposure to agrochemicals.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29235034</pmid><doi>10.1007/s11356-017-0969-z</doi><tpages>10</tpages></addata></record> |
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| ispartof | Environmental science and pollution research international, 2018-02, Vol.25 (6), p.5950-5959 |
| issn | 0944-1344 1614-7499 |
| language | eng |
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| source | ABI/INFORM Global; Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List |
| subjects | Adolescents Adults Agrochemicals Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution Biomarkers Children Cholesterol Chromatin Chromosome aberrations Crops Cytotoxicity Earth and Environmental Science Ecotoxicology Environment Environmental Chemistry Environmental Health Environmental science Exposure Genotoxicity Health risk assessment Health risks Horticultural crops Low density lipoprotein Lymphocytes Meat Parents Research Article Rural areas Teenagers Toxicity Triglycerides Tubers Waste Water Technology Water Management Water Pollution Control |
| title | Assessment of the health status and risk of genotoxic and cytotoxic damage in Argentinian adolescents living near horticultural crops |
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