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Three-component synthesis of 2-halo-6-methoxy-5,6-dihydropyridine-3,4,4(1H)-tricarbonitriles

One-stage preparation method of 2-halo-6-methoxy-5,6-dihydropyridine-3,4,4(1 H )-tricarbonitriles was developed, consisting in the reaction of 3,3-dialkyl-4-oxoalcane-1,1,2,2-tetracarbonitriles with hydrohalic acids in methanol.

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Published in:Russian journal of organic chemistry 2017-11, Vol.53 (11), p.1760-1762
Main Authors: Lipin, K. V., Ershov, O. V.
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description One-stage preparation method of 2-halo-6-methoxy-5,6-dihydropyridine-3,4,4(1 H )-tricarbonitriles was developed, consisting in the reaction of 3,3-dialkyl-4-oxoalcane-1,1,2,2-tetracarbonitriles with hydrohalic acids in methanol.
doi_str_mv 10.1134/S1070428017110288
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subjects Chemistry
Chemistry and Materials Science
Organic Chemistry
Short Communications
title Three-component synthesis of 2-halo-6-methoxy-5,6-dihydropyridine-3,4,4(1H)-tricarbonitriles
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