GS26PC REACTIVE PROTEIN IMPROVES DIAGNOSTIC ACCURACY OF ACUTE APPENDICITIS IN EQUIVOCAL CASES

The aim of the study was to evaluate whether C reactive protein level (CRP) on admission could aid the diagnostic accuracy of Alvarado score in acute appendicitis. Patients and methods : 233 patients (males 115, females 118, median age 28 years, range 15-87 years) who underwent appendicectomy were e...

Full description

Saved in:
Bibliographic Details
Published in:ANZ journal of surgery 2009-05, Vol.79 (s1), p.A30-A30
Main Authors: Thanavinthan thirumalai, S., Wijesuriya, R., Lim, S., Ong, S., Delriviere, L., Mitchell, A.
Format: Article
Language:English
Subjects:
Appendicitis
Medical diagnosis
Medical tests
Proteins
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The aim of the study was to evaluate whether C reactive protein level (CRP) on admission could aid the diagnostic accuracy of Alvarado score in acute appendicitis. Patients and methods : 233 patients (males 115, females 118, median age 28 years, range 15-87 years) who underwent appendicectomy were evaluated. Patients were categorized in to 3 groups retrospectively based on the Alvarado score. Group I: score 7-10 (n = 154), Group II: score 4-6 (n = 66), Group III: score < 3 (n = 13). Negative (NPV) and positive predictive values (PPV) of CRP which was performed at the time of admission was calculated. Overall, 169 of 233 (72.5%) had histopathological confirmation of acute appendicitis. In Group I it was 134 patients (87%), Group II: 35 patients (53%) and none of patients in Group III. NPV and PPV for Group I was 29.6% and 85.5%, Group II was 65% and 80% respectively. The CRP level improves the predictive value of diagnosing acute appendicitis in the equivocal group of Alvarado 4-6. Patients in this group with a normal CRP should be further investigated before proceeding to appendicectomy. [PUBLICATION ABSTRACT]
ISSN:1445-1433
1445-2197
DOI:10.1111/j.1445-2197.2009.04917_26.x