Severe type B lactic acidosis and insulin-resistant hyperglycemia related to cadaveric kidney transplantation

•Patients with end-stage renal disease are prone to thiamine deficiency.•Thiamine deficiency can cause severe type B lactic acidosis perioperatively.•Hemodialysis cannot correct lactate levels due to overproduction.•There is large variability in thiamine prescribing practices.•Intravenous thiamine r...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical anesthesia 2018-02, Vol.44, p.100-101
Main Authors: Souki, Fouad G., Ghaffaripour, Sina, Martinez-Lu, Kianfa, Mahmoudi, Hilda
Format: Article
Language:English
Subjects:
Acidosis, Lactic - etiology
Acidosis, Lactic - therapy
Blood Glucose
Conflicts of interest
Diabetes
Hemodialysis
Hemofiltration
Humans
Hyperglycemia
Hyperglycemia - blood
Hyperglycemia - drug therapy
Hyperglycemia - metabolism
Insulin
Insulin - therapeutic use
Ischemia
Kidney Failure, Chronic - complications
Kidney Failure, Chronic - therapy
Kidney transplantation
Kidney Transplantation - adverse effects
Kidney Transplantation - methods
Kidney transplants
Lactic Acid - blood
Lactic Acid - metabolism
Male
Metabolism
Middle Aged
Patients
Renal Dialysis
Renal replacement therapy
Thiamine - therapeutic use
Thiamine deficiency
Thiamine Deficiency - blood
Thiamine Deficiency - drug therapy
Thiamine Deficiency - etiology
Thiamine Deficiency - metabolism
Treatment Outcome
Type B lactic acidosis
Vitamin B
Vitamin deficiency
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•Patients with end-stage renal disease are prone to thiamine deficiency.•Thiamine deficiency can cause severe type B lactic acidosis perioperatively.•Hemodialysis cannot correct lactate levels due to overproduction.•There is large variability in thiamine prescribing practices.•Intravenous thiamine reverses thiamine deficiency lactic acidosis within hours.
ISSN:0952-8180
1873-4529
DOI:10.1016/j.jclinane.2017.11.024