Association of Serum Resistin with Indices of Obesity in Young Pakistani Subjects

The aim of this research work was to examine the relationship of serum resistin with metabolic markers in obese Pakistani subjects. Anthropometric parameters including age, body mass index (BMI), waist circumference, waist-hip ratio (WHR), diastolic and systolic blood pressure, lipid profile and fas...

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Bibliographic Details
Published in:Pakistan journal of zoology 2017-10, Vol.49 (5), p.1587-1593
Main Authors: Ashfaq, Farah, Farasat, Tasnim
Format: Article
Language:English
Subjects:
Anthropometry
Blood pressure
Body mass index
Body size
Body weight
Cholesterol
Cytokines
Developing countries
Diabetes
Fasting
Gene expression
Glucose
Glucose metabolism
Hip
Homeostasis
Hypertension
Inflammation
Insulin
Insulin resistance
LDCs
Markers
Metabolic disorders
Obesity
Observations
Overweight
Physiological aspects
Studies
Triglycerides
Young adults
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Summary:The aim of this research work was to examine the relationship of serum resistin with metabolic markers in obese Pakistani subjects. Anthropometric parameters including age, body mass index (BMI), waist circumference, waist-hip ratio (WHR), diastolic and systolic blood pressure, lipid profile and fasting glucose, serum resistin and insulin of three hundred over weight, obese males and females, 17 to 30 years and 100 comparable control subjects were included. Serum resistin and insulin, fasting glucose, triglycerides and cholesterol were found significantly high in overweight and obese groups as compared to the normal weight group (p < 0.01). In overweight group, resistin levels were significantly related with cholesterol, insulin levels and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) (r = 0.375, p =.000; r = 0.336, p < 0.01; r = 0.301, p < 0.01).In obese group, resistin showed a significant positive correlation with BMI, fasting glucose, systolic blood pressure and diastolic blood pressure (r = 0.332, p < 0.01; r = 0.278, p < 0.01; r =.279, p < 0.01 and r = 0.329, p < 0.01), respectively. To conclude this study suggests a positive association between serum resistin and metabolic markers of obesity in young Pakistani subjects.
ISSN:0030-9923
DOI:10.17582/journal.pjz/2017.49.5.1587.1593