Cu(II) immobilized on mesoporous organosilica as an efficient and reusable nanocatalyst for one‐pot Biginelli reaction under solvent‐free conditions

• Published in: Applied organometallic chemistry 2018-02, Vol.32 (2), p.n/a
• Main Authors: Nasresfahani, Zahra, Kassaee, Mohammad Zaman
• Format: Article
• Language: English
• Subjects: Biginelli reaction; Carbon dioxide; Catalysis; Catalysts; Catalytic activity; Chemical synthesis; Chemistry; Copper; Differential thermogravimetric analysis; Electron microscopy; Energy transmission; Fourier transforms; immobilized; Infrared spectroscopy; mesoporous organosilica; nanocatalyst; one‐pot synthesis; Scanning electron microscopy; Solvents; Thermal analysis; X-ray diffraction
• ISSN: 0268-2605; 1099-0739
• DOI: 10.1002/aoc.4106

Cu(II) immobilized on mesoporous organosilica nanoparticles (Cu2+@MSNs‐(CO2−)2) has been synthesized, as a inorganic–organic nanohybrid catalyst, through a post‐grafting approach. Its characterization is carried out by Fourier transform infrared spectroscopy (FT‐IR), X‐ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Energy dispersive X‐ray (EDX), Thermogravimetric/differential thermal analyses (TGA‐DTA), and Nitrogen adsorption–desorption analysis. Cu2+@MSNs‐(CO2−)2 exhibits high catalytic activity in the Biginelli reaction for the synthesis of a diverse range of 3, 4‐dihydropyrimidin‐2(1H)‐ones, under mild conditions. The anchored Cu(II) could not leach out from the surface of the mesoporous catalyst during the reaction and it has been reused several times without appreciable loss in its catalytic activity. Preparation and catalytic activity of Cu2+@MSNs‐(CO2−)2 in the Biginelli reaction for the synthesis of 3, 4‐dihydropyrimidin‐2(1H)‐ones.