Clinicopathological Profile and Treatment Outcomes of Bilateral Breast Cancer: A Study from Tertiary Cancer Center in South India

Abstract Background: Bilateral breast cancer (BBC) is a rare clinical entity with limited data regarding clinicopathological aspects and treatment guidelines. Materials and Methods: This was an observational study of patients diagnosed with BBC from August 2012 to July 2014. Synchronous breast cance...

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Bibliographic Details
Published in:Indian journal of medical and paediatric oncology 2018-01, Vol.39 (1), p.58-61
Main Authors: Jacob, Linu Abraham, Anand, Abhishek, Lakshmaiah, Kuntegowdanahalli C., Babu, Govind K., Lokanatha, Dasappa, Suresh Babu, M.C. Suresh, Lokesh, Kadabur N., Rudresha, Antapura Haleshappa, Rajeev, L K., Koppaka, Deepak
Format: Article
Language:English
Subjects:
Breast cancer
Cancer therapies
Care and treatment
Development and progression
Diagnosis
Family medical history
Guidelines
Health care
Health risk assessment
Mammography
Mastectomy
Original Article
Pathology
Patient outcomes
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Summary:Abstract Background: Bilateral breast cancer (BBC) is a rare clinical entity with limited data regarding clinicopathological aspects and treatment guidelines. Materials and Methods: This was an observational study of patients diagnosed with BBC from August 2012 to July 2014. Synchronous breast cancers (SBCs) was defined as two tumors diagnosed within an interval of 6 months and metachronous breast cancer (MBC) as second cancer diagnosed after 6 months. Results: Out of 750 breast cancer patients seen during a 2-year period, 35 had BBC. Ten patients were diagnosed as SBC whereas 25 patients as MBC. Among patients with MBC, the average time for development of contralateral breast cancer was 5 years. In 8 patients, the contralateral breast cancer was detected mammography whereas rest 27 patients were detected by clinical breast examination. At a median follow-up of 24 months, 23 (66%) patients were disease free, 9 (26%) patients had disease relapse, and 3 (8%) patients succumbed to the progressive disease. Conclusions: Every patient with breast cancer should be regularly followed up with clinical breast examination at a more frequent interval. The role of frequent clinical breast examination appears more than mammography especially beyond 5 years for early detection of contralateral breast cancer.
ISSN:0971-5851
0975-2129
DOI:10.4103/ijmpo.ijmpo_56_17