Overview on the synthetic routes to nicotine nitriles

The biological and medicinal properties of nicotinonitrile and its analogues have prompted enormous research aimed at developing synthetic routes to these heterocyclic. This review highlights the different synthetic routes to nicotine nitriles.

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Bibliographic Details
Published in:Synthetic communications 2018-02, Vol.48 (4), p.345-374
Main Authors: Salem, M. A., Helel, M. H., Gouda, M. A., Ammar, Y. A., El-Gaby, M. S. A.
Format: Article
Language:English
Subjects:
Biological properties
Chalcone
enaminone
enaminonitriles
Micheal addition
Nicotine
nicotinonitrile
Nitriles
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Description
Summary:The biological and medicinal properties of nicotinonitrile and its analogues have prompted enormous research aimed at developing synthetic routes to these heterocyclic. This review highlights the different synthetic routes to nicotine nitriles.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397911.2017.1394468