Antioxidant status in albino rats vaccinated against salmonellosis under chronic action of T-2 toxin and its correction by aminoseleton

The article represents the study of the effect of chronic intoxication with T-2 toxin on the antioxidant status of albino rats under their vaccination against salmonellosis. It is stated that the intensity of lipid peroxidation (LPO) processes increased under the action of toxin and led to increased...

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Bibliographic Details
Published in:Russian agricultural sciences 2017-11, Vol.43 (6), p.512-515
Main Authors: Shakhov, A. G., Shabunin, S. V., Vostroilova, G. A., Bliznetsova, G. N., Sashnina, L. Yu, Kantorovich, Yu. A.
Format: Article
Language:English
Subjects:
Agriculture
Albinism
Antioxidants
Biomedical and Life Sciences
Blood
Catalase
Chronic intoxication
Glutathione
Glutathione peroxidase
Intoxication
Life Sciences
Lipid peroxidation
Liver
Nitric oxide
Peroxidase
Peroxidation
Plant Biochemistry
Rats
Salmonellosis
Toxins
Vaccination
Veterinary
Vitamins
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Summary:The article represents the study of the effect of chronic intoxication with T-2 toxin on the antioxidant status of albino rats under their vaccination against salmonellosis. It is stated that the intensity of lipid peroxidation (LPO) processes increased under the action of toxin and led to increased content of toxic product, malonic dialdehyde (MDA), in blood and decreased indices of antioxidant protection (AOP), activity of glutathione peroxidase (GPO) and catalase enzymes and level of vitamins E and A, in liver and nitric oxide in blood serum. The application of aminoseleton promoted the lower level of LPO, decreased MDA in blood, and increased potential of enzymatic and nonenzymatic components of AOP.
ISSN:1068-3674
1934-8037
DOI:10.3103/S1068367417060143