RNA Biomarkers: Glycan Stimulation Enables Purification of Prostate Cancer Circulating Tumor Cells on PEDOT NanoVelcro Chips for RNA Biomarker Detection (Adv. Healthcare Mater. 3/2018)

In article number 1700701, Hsiao‐hua Yu and co‐workers purified circulating tumor cells (CTCs) from blood samples of prostate cancer (PCa) patients. This platform not only captures CTCs with high efficiency and specificity, but also, released these cells gently by a competitive‐binding mechanism. Th...

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Bibliographic Details
Published in:Advanced healthcare materials 2018-02, Vol.7 (3), p.n/a
Main Authors: Shen, Mo‐Yuan, Chen, Jie‐Fu, Luo, Chun‐Hao, Lee, Sangjun, Li, Cheng‐Hsuan, Yang, Yung‐Ling, Tsai, Yu‐Han, Ho, Bo‐Cheng, Bao, Li‐Rong, Lee, Tien‐Jung, Jan, Yu Jen, Zhu, Ya‐Zhen, Cheng, Shirley, Feng, Felix Y., Chen, Peilin, Hou, Shuang, Agopian, Vatche, Hsiao, Yu‐Sheng, Tseng, Hsian‐Rong, Posadas, Edwin M., Yu, Hsiao‐hua
Format: Article
Language:English
Subjects:
Biomarkers
Blood circulation
circulating tumor cells
Gene expression
Glycan
poly(3,4‐ethylene‐dioxythiophene)s
Prostate cancer
Purification
responsive materials
Ribonucleic acid
RNA
RNA biomarkers
Tumor cells
Workers
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Summary:In article number 1700701, Hsiao‐hua Yu and co‐workers purified circulating tumor cells (CTCs) from blood samples of prostate cancer (PCa) patients. This platform not only captures CTCs with high efficiency and specificity, but also, released these cells gently by a competitive‐binding mechanism. The purified CTCs provide well‐preserved RNA transcripts for the analysis of the expression level of several PCa‐specific RNA biomarkers, which could provide clinical insights into the disease and valuable information for cancer diagnosis and therapeutics.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.201870013