Green chemical multicomponent approach for the synthesis of C3-pyranopyrazole-substituted coumarins

An efficient and rapid method was developed for the synthesis of C3-pyranopyrazole-substituted coumarins from one-pot five-component reaction of β -keto ester, hydrazine, O -hydroxy aromatic aldehydes, 6-methyl, 4-hydroxy pyranone and aromatic aldehyde in the presence of tri-ethylamine in solvent-fr...

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Bibliographic Details
Published in:Journal of the Iranian Chemical Society 2018-04, Vol.15 (4), p.823-829
Main Authors: Tangeti, Venkata Swamy, Babu, Kattaru Ramesh, Siva Prasad, G. V., Ramu, Tadikonda, Venkata Rao, C.
Format: Article
Language:English
Subjects:
Aldehydes
Analytical Chemistry
Biochemistry
Chemical synthesis
Chemistry
Chemistry and Materials Science
Inorganic Chemistry
Organic Chemistry
Original Paper
Physical Chemistry
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Summary:An efficient and rapid method was developed for the synthesis of C3-pyranopyrazole-substituted coumarins from one-pot five-component reaction of β -keto ester, hydrazine, O -hydroxy aromatic aldehydes, 6-methyl, 4-hydroxy pyranone and aromatic aldehyde in the presence of tri-ethylamine in solvent-free conditions. The microwave-assisted method reported herein offers advantageous shorter reaction times, higher yields and cleaner reaction compared with conventional heating methods.
ISSN:1735-207X
1735-2428
DOI:10.1007/s13738-017-1281-z