Green chemical multicomponent approach for the synthesis of C3-pyranopyrazole-substituted coumarins

An efficient and rapid method was developed for the synthesis of C3-pyranopyrazole-substituted coumarins from one-pot five-component reaction of β -keto ester, hydrazine, O -hydroxy aromatic aldehydes, 6-methyl, 4-hydroxy pyranone and aromatic aldehyde in the presence of tri-ethylamine in solvent-fr...

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Published in:Journal of the Iranian Chemical Society 2018-04, Vol.15 (4), p.823-829
Main Authors: Tangeti, Venkata Swamy, Babu, Kattaru Ramesh, Siva Prasad, G. V., Ramu, Tadikonda, Venkata Rao, C.
Format: Article
Language:English
Subjects:
Aldehydes
Analytical Chemistry
Biochemistry
Chemical synthesis
Chemistry
Chemistry and Materials Science
Inorganic Chemistry
Organic Chemistry
Original Paper
Physical Chemistry
Substitutes
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description An efficient and rapid method was developed for the synthesis of C3-pyranopyrazole-substituted coumarins from one-pot five-component reaction of β -keto ester, hydrazine, O -hydroxy aromatic aldehydes, 6-methyl, 4-hydroxy pyranone and aromatic aldehyde in the presence of tri-ethylamine in solvent-free conditions. The microwave-assisted method reported herein offers advantageous shorter reaction times, higher yields and cleaner reaction compared with conventional heating methods.
doi_str_mv 10.1007/s13738-017-1281-z
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subjects Aldehydes
Analytical Chemistry
Biochemistry
Chemical synthesis
Chemistry
Chemistry and Materials Science
Inorganic Chemistry
Organic Chemistry
Original Paper
Physical Chemistry
Substitutes
title Green chemical multicomponent approach for the synthesis of C3-pyranopyrazole-substituted coumarins
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