Potency Of German Cockroach Extracts For IgE Reactivity Depends On Allergen Content And Allergen-specific IgE Titers Of The Cockroach Allergic Patient

Rationale This study addresses the significant variability in allergen content among different sources of cockroach extracts, which poses a challenge in terms of extract standardization for clinical use, and compares their potency for IgE reactivity in individual patients. Conclusions The potency of...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2018-02, Vol.141 (2), p.AB108-AB108
Main Authors: Glesner, Jill, Filep, Stephanie, Schulten, Véronique M., Frazier, April, Vailes, Lisa D., Wünschmann, Sabina, Leong, Kyoung Y., Schal, Coby, Chapman, Martin D., Sette, Alessandro, Pomés, Anna
Format: Article
Language:English
Subjects:
Allergens
Allergies
Blattella germanica
Cockroaches
Immunoglobulin E
Immunotherapy
Limulus
Patients
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Summary:Rationale This study addresses the significant variability in allergen content among different sources of cockroach extracts, which poses a challenge in terms of extract standardization for clinical use, and compares their potency for IgE reactivity in individual patients. Conclusions The potency of German cockroach extracts for IgE reactivity depends on allergen content and allergen-specific IgE titers of the cockroach allergic patient.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2017.12.344