Presence of Fragmented QRS and Its Relationship with Cardiac Functions in Patients with Obstructive Sleep Apnea

• Published in: Journal of the American College of Cardiology 2013-10, Vol.62 (18), p.C46-C47
• Main Authors: Adar, Adem, Kırış, Abdulkadir, Bülbül, Yılmaz, Bektaş, Hüseyin, Okutucu, Sercan, Acat, Murat, Casim, Hasan, Elönü, Hakan Orhan, Gökdeniz, Tayyar
• Format: Article
• Language: English
• Subjects: Age; Apnea; Body mass index; Cardiology; Cardiovascular; Diabetes; Electrocardiography; Enzymes; Heart diseases; Heart failure; Hypertension; Internal Medicine; Regression analysis; Sleep; Sleep apnea; Sleep disorders; Velocity
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2013.08.137

Multivariable regression analysis was performed to assess the independent relationship between fQRS and cardiac function in patients with OSA.Results Group 1 consisted of 121 patients (mean age 50.5±10) with OSA (26 mild, 31 moderate, 64 severe) and group 2 included 32 non-OSA patients (mean age 45.34±9). Baseline demographic features were similar such as gender (p=0.71), presence of hypertension (p=0.47), presence of diabetes (p=0.51), the usage of b-blocker (p=0.91), the usage of ACE inhibitor (p=0.53) and the body mass index (p=0.11). Group 1 FQRS (+) n=89 Group 2 FQRS (-) n=64 P-value Age (years) 51.86±9.31 47.22±10.60 0.018 Gender (male/female) 58/ 27 22/14 0.53 Hypertension, n(%) 30 (65.2%) 16 (34.8%) 0.41 Diabetes Mellitus, n(%) 10(58.8%) 7(41.2%) 0.26 Body mass index (kg/m2) 33.89±16 31.52±5.9 0.39 Apnea-hypopnea index (events/hour) 37.79±28.14 25.51±21.14 0.004 Lowest nocturnal oxygen saturation (%) 66.91±27.56 78.86±21.14 0.025 Length of time SpO2