P-wave and QT Dispersions for Predicting Early Death in Patients with Pulmonary Embolism

• Published in: Journal of the American College of Cardiology 2013-10, Vol.62 (18), p.C15-C16
• Main Authors: Akgüllü, Çağdaş, Eryılmaz, Ufuk, Dağtekin, Evrin, Akdeniz, Mehmet, Güngör, Hasan, Zencir, Cemil, Tekten, Tarkan, Onbaşılı, Osman Alper, Ceyhan, Ceyhun
• Format: Article
• Language: English
• Subjects: Cardiac arrhythmia; Cardiology; Cardiovascular; Chronic obstructive pulmonary disease; Diabetes; Electrocardiography; Embolism; Embolisms; Hypertension; Internal Medicine; Pulmonary arteries; Pulmonary embolisms; Thrombosis; Wave dispersion
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2013.08.055

P wave dispersion values of deaths were significantly higher than those who survived (73 (69,5-82,5) versus 51 (39,6-57,6) respectively, p=0,000). [...]QTcd values of deaths were also significantly higher than the survivors (119 (103-120) versus 76 (66,5-88,5) respectively, p=0,000). There was not any significant difference between the survivors and deaths by means of age, gender, smoking habit, D-dimer levels and accompanying diseases like diabetes, hypertension, malignity, chronic obstructive pulmonary disease (COPD) and deep venous thrombosis (p>0,05). Age 63 (51-75) Female sex 14 (%42,4) Male sex 19 (%57,6) Diabetes mellitus 17 (%51,5) Hypertension 23 (%69,7) Chronic obstructive pulmonary disease 10 (%30,3) Deep venous thrombosis 5 (%15,2) History of malignancy 3 (%9,1) Hemodynamic Instability 27 (%81,8) Total hospitalization time 8,39 (6,5-10) days Hospitalization to death time 6,5 (2-10) days Death 7 (%21,2) Survivors 26 (%78,8) Smoking 16 (%48,5) Thrombolytic therapy 5 (%15,2) Minor bleeding 4 (%12,1) Major bleeding 0 (%0) Troponin I 5 (0 – 1,3) mg/dl D-dimer 3800 (2054-5300) Hemogram 11,58 (10,65-12,9) QT dispersion 77 (68-94,3) P wave dispersion 55,5 (41,8-63,5) Longest P wave duration 104,5 (95,8-114,5) Shortest P wave duration 45,5 (41,5-54,5) Table 1 Deaths (n=7) Survivors (n=26) p Age 70(64-77) 62 (50-75) 0,330 Female Sex Male sex 2 (%28,6) 5 (%71,4) 12 (%46,2) 14 (%53,8) 0,670 Deep venous thrombosis 1 (%14,3) 4 (%15,4) 1,0 Diabetes mellitus 3 (%42,9) 14 (%53,8) 0,688 Hypertension 5 (%71,4) 18 (%69,2) 1,0 Chronic obstructive pulmonary disease 1 (%14,3) 9 (%34,6) 0,397 Malignancy 2 (%28,6) 1 (%3,8) 0,106 Smoking 5 (%71,4) 11 (%42,3) 0,225 Hemodynamic Instability 4 (%57,1) 23 (%88,5) 0,93 Corrected QT interval dispersion 119 (103-120) 76 (66,5-88,5) 0,000 P wave dispersion 73 (69,5-82,5) 51 (39,6-57,6) 0,000 Hemoglobin 10,6 (9-11,3) 12 (11-13,3) 0,034 Troponin I 17 (1,4-27) 0 (0,0-0,0) 0,01 D-dimer 5200 (3200-5800) 3650 (1600-5150) 0,268 Thrombolytic administered not-administered 2 (%28,6) 5 (%71,4) 3 (%11,5) 23 (%88,5) 0,282 Minor bleeding 1 (%14,3) 3 (%11,5) 1,0 Table 2