The potential of fucoidans from Chnoospora minima and Sargassum polycystum in cosmetics: antioxidant, anti-inflammatory, skin-whitening, and antiwrinkle activities

Over the years, bioactive and biocompatible natural products have received increased attention as ingredients of cosmeceutical formulations owing to their robust properties compared to many of the synthetic chemicals in use. Many natural products derived from algae have shown promising cosmetizing p...

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Bibliographic Details
Published in:Journal of applied phycology 2018-12, Vol.30 (6), p.3223-3232
Main Authors: Shanura Fernando, I. P., Asanka Sanjeewa, K. K., Samarakoon, Kalpa W., Kim, Hyun-Soo, Gunasekara, U. K. D. S. S., Park, Young-Jin, Abeytunga, D. T. U., Lee, Won Woo, Jeon, You-Jin
Format: Article
Language:English
Subjects:
8th Asian Pacific Phycological Forum
Algae
Analytical methods
Antioxidants
Biocompatibility
Biomedical and Life Sciences
Chnoospora minima
Collagen
Collagenase
Composition
Cosmetics
Ecology
Elastase
Formulations
Fourier transforms
Freshwater & Marine Ecology
Fucoidan
Inflammation
Infrared analysis
Life Sciences
Lipopolysaccharides
Macrophages
Melanin
Monosaccharides
Natural products
Plant Physiology
Plant Sciences
Polysaccharides
Properties
Saccharides
Sargassum polycystum
Seaweeds
Skin
Skin preparations
Sulfates
Tyrosinase
Ultraviolet radiation
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Summary:Over the years, bioactive and biocompatible natural products have received increased attention as ingredients of cosmeceutical formulations owing to their robust properties compared to many of the synthetic chemicals in use. Many natural products derived from algae have shown promising cosmetizing properties. Seaweed polysaccharides, in particular, have received increased attention for their biofunctional and physicochemical characteristics. This study aimed to design a cost-effective strategy to purify fucoidans from the untapped brown algae Chnoospora minima (CMF) and Sargassum polycystum (SPF) harvested in Sri Lanka and to evaluate their cosmetizing properties. Based on Fourier transform infrared (FTIR) spectroscopy and monosaccharide composition analysis, the purified polysaccharides were rich in fucoidan. Relatively high sulfate content was detected in both fucoidans. Experiments were carried out to evaluate antioxidant, UV-protective, anti-inflammatory, antiwrinkling, and skin-whitening effects. Both CMF and SPF showed 2,2-diphenyl-1-picrylhydrazyl (DPPH) and alkyl radical-scavenging activities, anti-inflammatory effects on lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages, considerable collagenase and elastase inhibitory properties and skin-whitening effects via direct inhibition of tyrosinase, and intracellular melanin synthesis indicating promising cosmetizing effects.
ISSN:0921-8971
1573-5176
DOI:10.1007/s10811-018-1415-4