Testicular and paratesticular tumours in the prepubertal population

Summary Prepubertal testicular and paratesticular tumours are a rare group of tumours, distinct from postpubertal paediatric and adult tumours of this region. Tumours within this group are testicular germ-cell tumours (such as benign teratoma, epidermoid cyst and malignant yolk-sac tumours) and stro...

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Bibliographic Details
Published in:The lancet oncology 2010-05, Vol.11 (5), p.476-483
Main Authors: Ahmed, Hashim U, MRCS, Arya, Manit, FRCS, Muneer, Asif, FRCS, Mushtaq, Imran, FRCS, Sebire, Neil J, Prof
Format: Article
Language:English
Subjects:
Age
Cancer
Child
Children & youth
Combined Modality Therapy
Cysts
Epidemiology
Genital Neoplasms, Male - diagnosis
Genital Neoplasms, Male - epidemiology
Genital Neoplasms, Male - therapy
Hematology, Oncology and Palliative Medicine
Hernias
Humans
Male
Neoplasm Staging
Neoplasms, Germ Cell and Embryonal - diagnosis
Neoplasms, Germ Cell and Embryonal - epidemiology
Neoplasms, Germ Cell and Embryonal - therapy
Oncology
Pathology
Pediatrics
Sex Cord-Gonadal Stromal Tumors - diagnosis
Sex Cord-Gonadal Stromal Tumors - epidemiology
Sex Cord-Gonadal Stromal Tumors - therapy
Testicular Neoplasms - diagnosis
Testicular Neoplasms - epidemiology
Testicular Neoplasms - therapy
Tumors
Ultrasonic imaging
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Summary:Summary Prepubertal testicular and paratesticular tumours are a rare group of tumours, distinct from postpubertal paediatric and adult tumours of this region. Tumours within this group are testicular germ-cell tumours (such as benign teratoma, epidermoid cyst and malignant yolk-sac tumours) and stromal tumours (such as juvenile granulosa-cell, leydig-cell, and sertoli-cell tumours). Paratesticular tumours can be benign (lipoma, leiomyoma, haemangioma) or malignant (rhabdomyosarcoma, melanotic neuroectodermal tumour of infancy). Because of their rarity, centralised pathology and treatment, and national collaborative clinical trials have been important in establishing the optimum management of malignant tumours in this group. We provide an up-to-date and comprehensive review of the clinical presentation, imaging, pathology, and clinical management of prepubertal paratesticular and testicular tumours.
ISSN:1470-2045
1474-5488
DOI:10.1016/S1470-2045(10)70012-7