Loading…
Ozone exposure and blood antioxidants: A study in periurban area in southern France
Major carotenoids in plasma--especially beta-carotene--are affected by oxidative stress (e.g., tobacco smoking). Environmental ozone induced oxidative stress in experimental in vitro and in vivo studies, and it also increased the incidence of lung cancer in mice. We proposed to measure, after contro...
Saved in:
Published in: | Archives of environmental & occupational health 1999-01, Vol.54 (1), p.34 |
---|---|
Main Authors: | , , , |
Format: | Article |
Language: | English |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | |
---|---|
cites | |
container_end_page | |
container_issue | 1 |
container_start_page | 34 |
container_title | Archives of environmental & occupational health |
container_volume | 54 |
creator | Saintot, Monique Bernard, Nadine Astre, Cecile Gerber, Mariette |
description | Major carotenoids in plasma--especially beta-carotene--are affected by oxidative stress (e.g., tobacco smoking). Environmental ozone induced oxidative stress in experimental in vitro and in vivo studies, and it also increased the incidence of lung cancer in mice. We proposed to measure, after controlling for other determinants, the impact of personal ozone exposure on carotenoids levels in plasma. During the summer, we recruited 58 volunteer subjects who worked in a periurban zone. We asked each subject to wear a passive sample, which measured ozone exposure for 5 consecutive d. At the end of this period, we assessed plasma antioxidants. We observed a negative significant regression coefficient between alpha- or beta-carotene and ozone exposure (r = -.39, p < .01, and r = -.45, p = .02, respectively). In a subsample of 45 nonsmoker subjects, among whom carotene intake was lower than the median intake value (i.e., 6.6 mg/d) of the overall group, we noted that a relatively low exposure to ozone (> or = 50 microg/m3 x h or > or = 23.8 ppb) induced a significant decrease in plasma beta-carotene levels (i.e., 0.7 micromol/l to 0.4 micromol/l). This significant decrease suggested that a high dietary intake of fruit or vegetables can have a beneficial influence on the levels of plasma antioxidants generated in response to ozone exposure. |
format | article |
fullrecord | <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_journals_201246044</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>38525308</sourcerecordid><originalsourceid>FETCH-proquest_journals_2012460443</originalsourceid><addsrcrecordid>eNqNissKwjAQRYMoWB__MLgvpGm01p2IxZ0L3ZfUjJhSMjVpoPr1VvADXJ3LuWfEIpGsZSwzzscsSvI0jbdCyimbeV9zLjORi4hdzm-yCNi35INDUFZD1RDpYXWGeqMH-h3swXdBv8BYaNGZ4CplQTlUX-MpdA90Fgqn7A0XbHJXjcflj3O2Ko7XwyluHT0D-q6sKTg7XKXgiZAbLmX6V_QBxGNAzg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>201246044</pqid></control><display><type>article</type><title>Ozone exposure and blood antioxidants: A study in periurban area in southern France</title><source>Taylor and Francis Science and Technology Collection</source><creator>Saintot, Monique ; Bernard, Nadine ; Astre, Cecile ; Gerber, Mariette</creator><creatorcontrib>Saintot, Monique ; Bernard, Nadine ; Astre, Cecile ; Gerber, Mariette</creatorcontrib><description>Major carotenoids in plasma--especially beta-carotene--are affected by oxidative stress (e.g., tobacco smoking). Environmental ozone induced oxidative stress in experimental in vitro and in vivo studies, and it also increased the incidence of lung cancer in mice. We proposed to measure, after controlling for other determinants, the impact of personal ozone exposure on carotenoids levels in plasma. During the summer, we recruited 58 volunteer subjects who worked in a periurban zone. We asked each subject to wear a passive sample, which measured ozone exposure for 5 consecutive d. At the end of this period, we assessed plasma antioxidants. We observed a negative significant regression coefficient between alpha- or beta-carotene and ozone exposure (r = -.39, p < .01, and r = -.45, p = .02, respectively). In a subsample of 45 nonsmoker subjects, among whom carotene intake was lower than the median intake value (i.e., 6.6 mg/d) of the overall group, we noted that a relatively low exposure to ozone (> or = 50 microg/m3 x h or > or = 23.8 ppb) induced a significant decrease in plasma beta-carotene levels (i.e., 0.7 micromol/l to 0.4 micromol/l). This significant decrease suggested that a high dietary intake of fruit or vegetables can have a beneficial influence on the levels of plasma antioxidants generated in response to ozone exposure.</description><identifier>ISSN: 1933-8244</identifier><identifier>EISSN: 2154-4700</identifier><language>eng</language><publisher>Washington: Kirkpatrick Jordon Foundation</publisher><ispartof>Archives of environmental & occupational health, 1999-01, Vol.54 (1), p.34</ispartof><rights>Copyright Heldref Publications Jan/Feb 1999</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Saintot, Monique</creatorcontrib><creatorcontrib>Bernard, Nadine</creatorcontrib><creatorcontrib>Astre, Cecile</creatorcontrib><creatorcontrib>Gerber, Mariette</creatorcontrib><title>Ozone exposure and blood antioxidants: A study in periurban area in southern France</title><title>Archives of environmental & occupational health</title><description>Major carotenoids in plasma--especially beta-carotene--are affected by oxidative stress (e.g., tobacco smoking). Environmental ozone induced oxidative stress in experimental in vitro and in vivo studies, and it also increased the incidence of lung cancer in mice. We proposed to measure, after controlling for other determinants, the impact of personal ozone exposure on carotenoids levels in plasma. During the summer, we recruited 58 volunteer subjects who worked in a periurban zone. We asked each subject to wear a passive sample, which measured ozone exposure for 5 consecutive d. At the end of this period, we assessed plasma antioxidants. We observed a negative significant regression coefficient between alpha- or beta-carotene and ozone exposure (r = -.39, p < .01, and r = -.45, p = .02, respectively). In a subsample of 45 nonsmoker subjects, among whom carotene intake was lower than the median intake value (i.e., 6.6 mg/d) of the overall group, we noted that a relatively low exposure to ozone (> or = 50 microg/m3 x h or > or = 23.8 ppb) induced a significant decrease in plasma beta-carotene levels (i.e., 0.7 micromol/l to 0.4 micromol/l). This significant decrease suggested that a high dietary intake of fruit or vegetables can have a beneficial influence on the levels of plasma antioxidants generated in response to ozone exposure.</description><issn>1933-8244</issn><issn>2154-4700</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><recordid>eNqNissKwjAQRYMoWB__MLgvpGm01p2IxZ0L3ZfUjJhSMjVpoPr1VvADXJ3LuWfEIpGsZSwzzscsSvI0jbdCyimbeV9zLjORi4hdzm-yCNi35INDUFZD1RDpYXWGeqMH-h3swXdBv8BYaNGZ4CplQTlUX-MpdA90Fgqn7A0XbHJXjcflj3O2Ko7XwyluHT0D-q6sKTg7XKXgiZAbLmX6V_QBxGNAzg</recordid><startdate>19990101</startdate><enddate>19990101</enddate><creator>Saintot, Monique</creator><creator>Bernard, Nadine</creator><creator>Astre, Cecile</creator><creator>Gerber, Mariette</creator><general>Kirkpatrick Jordon Foundation</general><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>MBDVC</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>S0X</scope></search><sort><creationdate>19990101</creationdate><title>Ozone exposure and blood antioxidants: A study in periurban area in southern France</title><author>Saintot, Monique ; Bernard, Nadine ; Astre, Cecile ; Gerber, Mariette</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_journals_2012460443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saintot, Monique</creatorcontrib><creatorcontrib>Bernard, Nadine</creatorcontrib><creatorcontrib>Astre, Cecile</creatorcontrib><creatorcontrib>Gerber, Mariette</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>eLibrary</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Family Health</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest research library</collection><collection>ProQuest Science Journals</collection><collection>Research Library (Corporate)</collection><collection>Environmental Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><jtitle>Archives of environmental & occupational health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saintot, Monique</au><au>Bernard, Nadine</au><au>Astre, Cecile</au><au>Gerber, Mariette</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ozone exposure and blood antioxidants: A study in periurban area in southern France</atitle><jtitle>Archives of environmental & occupational health</jtitle><date>1999-01-01</date><risdate>1999</risdate><volume>54</volume><issue>1</issue><spage>34</spage><pages>34-</pages><issn>1933-8244</issn><eissn>2154-4700</eissn><abstract>Major carotenoids in plasma--especially beta-carotene--are affected by oxidative stress (e.g., tobacco smoking). Environmental ozone induced oxidative stress in experimental in vitro and in vivo studies, and it also increased the incidence of lung cancer in mice. We proposed to measure, after controlling for other determinants, the impact of personal ozone exposure on carotenoids levels in plasma. During the summer, we recruited 58 volunteer subjects who worked in a periurban zone. We asked each subject to wear a passive sample, which measured ozone exposure for 5 consecutive d. At the end of this period, we assessed plasma antioxidants. We observed a negative significant regression coefficient between alpha- or beta-carotene and ozone exposure (r = -.39, p < .01, and r = -.45, p = .02, respectively). In a subsample of 45 nonsmoker subjects, among whom carotene intake was lower than the median intake value (i.e., 6.6 mg/d) of the overall group, we noted that a relatively low exposure to ozone (> or = 50 microg/m3 x h or > or = 23.8 ppb) induced a significant decrease in plasma beta-carotene levels (i.e., 0.7 micromol/l to 0.4 micromol/l). This significant decrease suggested that a high dietary intake of fruit or vegetables can have a beneficial influence on the levels of plasma antioxidants generated in response to ozone exposure.</abstract><cop>Washington</cop><pub>Kirkpatrick Jordon Foundation</pub></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1933-8244 |
ispartof | Archives of environmental & occupational health, 1999-01, Vol.54 (1), p.34 |
issn | 1933-8244 2154-4700 |
language | eng |
recordid | cdi_proquest_journals_201246044 |
source | Taylor and Francis Science and Technology Collection |
title | Ozone exposure and blood antioxidants: A study in periurban area in southern France |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T13%3A55%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Ozone%20exposure%20and%20blood%20antioxidants:%20A%20study%20in%20periurban%20area%20in%20southern%20France&rft.jtitle=Archives%20of%20environmental%20&%20occupational%20health&rft.au=Saintot,%20Monique&rft.date=1999-01-01&rft.volume=54&rft.issue=1&rft.spage=34&rft.pages=34-&rft.issn=1933-8244&rft.eissn=2154-4700&rft_id=info:doi/&rft_dat=%3Cproquest%3E38525308%3C/proquest%3E%3Cgrp_id%3Ecdi_FETCH-proquest_journals_2012460443%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=201246044&rft_id=info:pmid/&rfr_iscdi=true |