Loss of retinoic acid receptor (gamma) function in F9 cells by gene disruption results in aberrant Hoxa-1 expression and differentiation upon retinoic acid treatment

The results of a study support the idea that each retinoic acid receptor (RAR) may regulate different subsets of RA-responsive genes. This may explain, in part, the complex regulation of developmental processes by retinoids.

Saved in:
Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 1993-10, Vol.90 (20), p.9601
Main Authors: Boylan, John F, Lohnes, David, Taneja, Reshma, Chambon, Pierre, Gudas, Lorraine J
Format: Article
Language:English
Subjects:
Cellular biology
Genes
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The results of a study support the idea that each retinoic acid receptor (RAR) may regulate different subsets of RA-responsive genes. This may explain, in part, the complex regulation of developmental processes by retinoids.
ISSN:0027-8424
1091-6490