Does cesarean section prevent mortality and cerebral ultrasound abnormalities in preterm newborns?

Objective. Despite the increased use of the cesarean section (CS), the rates of cerebral palsy, a frequent consequence of brain damage, have remained stable over the last decades. Whether an actual decrease in cerebral palsy has been masked by increased survival of infants delivered by CS or not, re...

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Published in:The journal of maternal-fetal & neonatal medicine 2007-02, Vol.20 (2), p.151-159
Main Authors: Arpino, Carla, Brescianini, Sonia, Ticconi, Carlo, Di Paolo, Ambrogio, D'argenzio, Luigi, Piccione, Emilio, Curatolo, Paolo
Format: Article
Language:English
Subjects:
Brain Damage, Chronic - mortality
Brain Damage, Chronic - prevention & control
Cerebellum - abnormalities
Cerebellum - diagnostic imaging
cerebral ultrasound abnormalities
Cerebrovascular Disorders - mortality
Cerebrovascular Disorders - prevention & control
Cesarean Section
Delivery, Obstetric
Echoencephalography
Female
Gestational Age
Humans
Infant Mortality
Infant, Newborn
Infant, Premature
Longitudinal Studies
Male
mode of delivery
mortality
Odds Ratio
Pregnancy
Preterm newborns
Retrospective Studies
Risk Factors
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Summary:Objective. Despite the increased use of the cesarean section (CS), the rates of cerebral palsy, a frequent consequence of brain damage, have remained stable over the last decades. Whether an actual decrease in cerebral palsy has been masked by increased survival of infants delivered by CS or not, remains undefined. To investigate the role of CS, we compared risks of mortality and brain damage, as defined by ultrasound (US) abnormalities, in preterm newborns by mode of delivery. Methods. Information on fetal, maternal, and neonatal risk factors was collected from the paired clinical records of preterm newborns and mothers. Crude and adjusted odds ratios (OR) of mortality and ultrasound abnormalities, according to mode of delivery (i.e., vaginal, elective CS, and emergency CS) were calculated. All the analyses were controlled for possible confounding by indication. Results. In newborns of gestational age
ISSN:1476-7058
1476-4954
DOI:10.1080/14767050601133662