MLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steriodogenesis

Mutations that inactivate the steroidogenic acute regulatory protein (StAR) were correlated with amino acid residues that are identical or similar among StAR and MLN64, indicating that conserved motifs are important for steroidogenic activity.

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 1997-08, Vol.94 (16), p.8462
Main Authors: Watari, Hidemichi, Arakane, Futoshi, Moog-Lutz, Christel, Kallen, Caleb B
Format: Article
Language:English
Subjects:
Amino acids
Biochemistry
Cholesterol
Mutation
Proteins
Online Access:Get full text
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Description
Summary:Mutations that inactivate the steroidogenic acute regulatory protein (StAR) were correlated with amino acid residues that are identical or similar among StAR and MLN64, indicating that conserved motifs are important for steroidogenic activity.
ISSN:0027-8424
1091-6490