Noninvasive imaging of protein-protein interactions in livin animals

Protein-protein interactions control transcription, cell division, and cell proliferation as well as mediate signal transduction, oncogenic transformation, and regulation of cell death. Although a variety of methods have been used to investigate protein interactions in vitro and in cultured cells, n...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 2002-05, Vol.99 (10), p.6961
Main Authors: Luker, Gary D, Sharma, Vijay, Pica, Christina M, Dahlheimer, Julie L
Format: Article
Language:English
Subjects:
Animals
Cells
Medical imaging
Proteins
Studies
Online Access:Get full text
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Summary:Protein-protein interactions control transcription, cell division, and cell proliferation as well as mediate signal transduction, oncogenic transformation, and regulation of cell death. Although a variety of methods have been used to investigate protein interactions in vitro and in cultured cells, none can analyze these interactions in intact, living animals.
ISSN:0027-8424
1091-6490