The mode of action and the structure of a herbicide in complex with its target: Binding of activate hydantocidin to the feedback regulation site of adenylosuccinate synthetase

Hydantocidin, a recently discovered natural spironculeoside with potent herbicidal activity, is shown in a study to be a proherbicide that, after phosphorylation at the 5' position, inhibits adenylosuccinate synthetase.

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 1996-09, Vol.93 (18), p.9431
Main Authors: Fonne-Pfister, R, Chemla, P, Ward, E, Girardet, M
Format: Article
Language:English
Subjects:
Enzymes
Herbicides
Online Access:Get full text
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Summary:Hydantocidin, a recently discovered natural spironculeoside with potent herbicidal activity, is shown in a study to be a proherbicide that, after phosphorylation at the 5' position, inhibits adenylosuccinate synthetase.
ISSN:0027-8424
1091-6490