The nonpeptide WIN 64338 is a bradykinin B(2) receptor antagonist

The synthesis and in vitro biological activity of the nonpeptide bradykinin receptor antagonist WIN 64338 are discussed. Synthesis of WIN 64338 provides a nonpeptide competitive bradykinin B2 antagonist active in both bradykinin radioligand binding and functional assays.

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Published in:Proceedings of the National Academy of Sciences - PNAS 1994-05, Vol.91 (11), p.4693
Main Authors: Sawutz, David G, Salvino, Joseph M, Dolle, Roland E, Casiano, Fran
Format: Article
Language:English
Subjects:
Biochemistry
Pharmacology
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container_title Proceedings of the National Academy of Sciences - PNAS
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creator Sawutz, David G
Salvino, Joseph M
Dolle, Roland E
Casiano, Fran
description The synthesis and in vitro biological activity of the nonpeptide bradykinin receptor antagonist WIN 64338 are discussed. Synthesis of WIN 64338 provides a nonpeptide competitive bradykinin B2 antagonist active in both bradykinin radioligand binding and functional assays.
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ispartof Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (11), p.4693
issn 0027-8424
1091-6490
language eng
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source JSTOR Archival Journals and Primary Sources Collection; PubMed Central
subjects Biochemistry
Pharmacology
title The nonpeptide WIN 64338 is a bradykinin B(2) receptor antagonist
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