Frequency of echogenic intracardiac focus by race/ethnicity in euploid fetuses

Objective. To determine the frequency of echogenic intracardiac focus (EIF) by race/ethnicity. Methods. We performed a retrospective analysis from January 1996 through June 2003. We reviewed all initial sonograms from 14 to 23 weeks gestation in singleton pregnancies. Mothers on admission for delive...

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Bibliographic Details
Published in:The journal of maternal-fetal & neonatal medicine 2005-07, Vol.18 (1), p.65-66
Main Authors: Borgida, Adam F, Maffeo, Christine, Gianferarri, Elisa A, Bolnick, Alan D, Zelop, Carolyn M, Egan, James FX
Format: Article
Language:English
Subjects:
African Americans
Asian Americans
Echogenic intracardiac focus
European Continental Ancestry Group
Female
Fetal Diseases - diagnostic imaging
Fetal Diseases - epidemiology
Fetal Diseases - ethnology
Fetal Heart - diagnostic imaging
Hispanic Americans
Humans
Pregnancy
race/ethnicity
Retrospective Studies
Ultrasonography, Prenatal
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Summary:Objective. To determine the frequency of echogenic intracardiac focus (EIF) by race/ethnicity. Methods. We performed a retrospective analysis from January 1996 through June 2003. We reviewed all initial sonograms from 14 to 23 weeks gestation in singleton pregnancies. Mothers on admission for delivery provided race/ethnicity. Results. There were 8207 ultrasounds and deliveries that met study criteria. There were 4636 (56.5%) Caucasian, 2087 (25.4%) African-American, 1261 (15.4%) Hispanic and 223 (2.7 %) Asian subjects. There were 347 (4.2%) EIF detected. The frequency by race/ethnicity varied significantly (p < 0.0001). Conclusions. This large, population-based study showed that fetuses born to Asian mothers were significantly more likely to have an EIF. This racial difference should be taken into account when counseling patients about the potential for Down syndrome.
ISSN:1476-7058
1476-4954
DOI:10.1080/14767050500073100